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It is also possible that repeated administration of bupropion is required to increase striatal dopamine concentrations in man; this hypothesis could be tested using a similar 11 c raclopride pet approach to the present study.

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you should know that bupropion may cause angle-closure glaucoma a condition where the fluid is suddenly blocked and unable to flow out of the eye causing a quick, severe increase in eye pressure which may lead to a loss of vision .

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if bupropion is used concomitantly with a cyp inducer, it may be necessary to increase the dose of bupropion but the maximum recommended dose should not be exceeded.

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the use of bupropion within 14 days of discontinuing treatment with an maoi is also contraindicated.

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